Data integrity on microcomputers

[Dave Fenske]

Since micros are somewhat simpler internally than larger computers, does anyone
have any thoughts on the integrity with which data is stored and/or manipulated?

As an example, micros have a simple parity check in memory where larger a 
larger computer might have ECC.  Also, the methods of checking data which is
read off of disk, etc.

In short, could a microcomputer be used in very sensitive applications?

I'd appreciate any and all opinions.  Thanks.

DF